Group by Gene: Include preclinical: Chemotherapy Other CD Protein Inhibitors Immune Checkpoint Inhibitors Immunotherapy BCL Inhibitors DNA PARP Inhibitors Serine-Threonine Kinase Inhibitors Threonine-Tyrosine Kinase Inhibitors EGFR Tyrosine Kinase Inhibitors | Bifunctional alkylating agent ifosfamide | Topoisomerase II inhibitor etoposide IV | Topoisomerase II inhibitor, RNA synthesis inhibitor dactinomycin | PD1 inhibitor camrelizumab | pembrolizumab | PARP inhibitor olaparib | mTOR inhibitor everolimus | EGFR inhibitor icotinib | VIP | EP | BEP | CaT | Chemotherapy TI-CE | GemOx | VC | VAC | VeIP | TIP | MEK inhibitor MEK inhibitor | Microtubule stabilizer, Tubulin polymerization promoter carboplatin + docetaxel | docetaxel | Tubulin polymerization promoter, DNA synthesis inhibitor, Bcl2 inhibitor gemcitabine + paclitaxel | Tubulin polymerization promoter, Bcl2 inhibitor paclitaxel | Bifunctional alkylating agent, Tubulin polymerization promoter, Bcl2 inhibitor paclitaxel + ifosfamide | Tubulin polymerization promoter, DNA synthesis inhibitor, DNA cross linking agent, Bcl2 inhibitor gemcitabine + paclitaxel + oxaliplatin | Bifunctional alkylating agent, Topoisomerase II inhibitor, DNA inhibitor, DNA synthesis inhibitor cisplatin + ifosfamide + etoposide oral | Topoisomerase II inhibitor, DNA inhibitor etoposide oral | DNA synthesis inhibitor cisplatin |
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No biomarker | ||||||||||||||||||||||||||||
MSI-H/dMMR | ||||||||||||||||||||||||||||
BRCA2 mutation | ||||||||||||||||||||||||||||
PMS2 mutation | ||||||||||||||||||||||||||||
MTOR mutation | ||||||||||||||||||||||||||||
TMB-H | ||||||||||||||||||||||||||||
MSH6 mutation | ||||||||||||||||||||||||||||
KRAS amplification | ||||||||||||||||||||||||||||
EGFR L858R | ||||||||||||||||||||||||||||
BRCA1 mutation | ||||||||||||||||||||||||||||
BRCA1 expression | ||||||||||||||||||||||||||||
Chr t(22) | ||||||||||||||||||||||||||||
BAX underexpression | ||||||||||||||||||||||||||||
XPA expression | ||||||||||||||||||||||||||||
RAD51C expression | ||||||||||||||||||||||||||||
TP53 mutation | ||||||||||||||||||||||||||||
PLAC8 overexpression |