^
CANCER:

Gastrointestinal Stromal Tumor





Show legend
Group by Gene:
Include preclinical:

regorafenib
0
Multi-tyrosine kinase inhibitor
cabozantinib tablet
pazopanib
ponatinib
1
Bcr-abl tyrosine kinase inhibitor
nilotinib
olverembatinib
2
PDGFR antagonist, mutant c-KIT inhibitor
avapritinib
3
HSP90 inhibitor
pimitespib
IPI 493
4
TrkB receptor inhibitor, TrkC kinase inhibitor, TrkA receptor inhibitor
larotrectinib
5
DNA synthesis inhibitor
temozolomide
6
PDGFR β inhibitor, PDGFR α inhibitor
ARO-002
7
PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, c-KIT inhibitor
imatinib
8
PDGFR α inhibitor, c-KIT inhibitor, FLT3 inhibitor
ripretinib
9
Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
dasatinib
10
VEGFR inhibitor, PDGFR inhibitor, c-KIT inhibitor
sunitinib
sunitinib + PLX9486
11
pan-RAF inhibitor, Multi-tyrosine kinase inhibitor
sorafenib
12
TrkB receptor inhibitor, TrkC kinase inhibitor, ROS1 inhibitor, TrkA receptor inhibitor, ALK inhibitor
entrectinib
13
GPR20 -targeted antibody-drug conjugate, Topoisomerase I inhibitor
DS-6157
14
PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, mTOR inhibitor, c-KIT inhibitor
imatinib + everolimus
15
Tubulin binding agent, Microtubule inhibitor
PM184
16
WEE1 inhibitor
AZD1775
17
PDGFR antagonist, mutant c-KIT inhibitor, WEE1 inhibitor
AZD1775 + avapritinib
18
VEGFR inhibitor, HSP90 inhibitor, PDGFR inhibitor, c-KIT inhibitor
sunitinib + IPI 493
19
FGFR inhibitor, PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, c-KIT inhibitor
imatinib + infigratinib
No biomarker
KIT mutation
KIT exon 11 mutation
KIT exon 17 mutation
KIT exon 13 mutation
KIT exon 9 mutation
KIT exon 18 mutation
KIT exon 14 mutation
KIT positive
KIT expression
KIT exon 11 mutation + KIT exon 17 mutation
KIT N822K
KIT N820Y
KIT V560E
KIT V559_E561del
KIT M552_V555delMYEV
KIT W557_V559>F
KIT W557_V559>C
KIT V654A
KIT Y823D
KIT N822Y
KIT D820A
KIT D820G
KIT D820Y
KIT exon 17 mutation + KIT exon 18 mutation
KIT wild-type
KIT P577del + KIT W557Lfs*5 + KIT Y823D
KIT W557_V559delinsF
KIT exon 11 W557_K558delins
KIT D818Y
PDGFRA D842V
PDGFRA mutation
PDGFRA exon 18 mutation
PDGFRA I843_D846delIMHD
NTRK3 fusion
SDHB mutation
SDHB deletion
NTRK1 fusion
NTRK2 fusion
CDK4 overexpression
DEPDC5 deletion
KIT wild-type + SDHB deletion
SDHC mutation
TMEM127 mutation
SRC mutation
TP53 mutation
APC mutation
KIT positive + CD34 positive + ANO1 positive + ACTA2 positive
SDHB mutation + NF1 mutation
TP53 overexpression
FGF2-H
GPR20 expression
TEKT4 mutation
SUFU mutation
BRAF V600E
MDM2 overexpression