^
    CANCER:

    Gastrointestinal Stromal Tumor





    Show legend
    Group by Gene:
    Include preclinical:

    regorafenib
    pazopanib
    		0
    Multi-tyrosine kinase inhibitor
    ponatinib
    cabozantinib tablet
    anlotinib
    1
    Bcr-abl tyrosine kinase inhibitor
    nilotinib
    olverembatinib
    2
    HSP90 inhibitor
    pimitespib
    IPI 493
    3
    TrkB receptor inhibitor, TrkC kinase inhibitor, TrkA receptor inhibitor
    larotrectinib
    4
    MEK inhibitor, BRAF inhibitor
    trametinib + dabrafenib
    5
    PARP inhibitor
    rucaparib
    6
    DNA synthesis inhibitor
    temozolomide
    7
    HER2 inhibitor, γδ TCR modulator
    Undisclosed allogeneic Vγ9Vδ2 HER2-TAC T
    8
    PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, c-KIT inhibitor
    imatinib
    9
    PDGFR α inhibitor, c-KIT inhibitor, FLT3 inhibitor
    ripretinib
    10
    VEGFR inhibitor, PDGFR inhibitor, c-KIT inhibitor
    sunitinib
    sunitinib + PLX9486
    11
    Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
    dasatinib
    12
    MEK inhibitor
    binimetinib
    13
    pan-RAF inhibitor, Multi-tyrosine kinase inhibitor
    sorafenib
    14
    PDGFR antagonist, mutant c-KIT inhibitor, CSF-1R inhibitor
    avapritinib
    15
    TrkB receptor inhibitor, TrkC kinase inhibitor, ROS1 inhibitor, TrkA receptor inhibitor, ALK inhibitor, JAK2 inhibitor, TNK2 inhibitor
    entrectinib
    16
    GPR20 -targeted antibody-drug conjugate, Topoisomerase I inhibitor
    DS-6157
    17
    PDGFR β inhibitor, PDGFR α inhibitor, FLT3 inhibitor
    ARO-002
    18
    VEGFR inhibitor, PD1 inhibitor
    sintilimab + fruquintinib
    19
    PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, mTOR inhibitor, c-KIT inhibitor
    imatinib + everolimus
    20
    WEE1 inhibitor
    AZD1775
    21
    c-KIT-targeted antibody-drug conjugate, Microtubule inhibitor
    LOP628
    22
    Tubulin binding agent, Microtubule inhibitor
    PM184
    23
    VEGFR inhibitor, HSP90 inhibitor, PDGFR inhibitor, c-KIT inhibitor
    sunitinib + IPI 493
    24
    PDGFR antagonist, mutant c-KIT inhibitor, CSF-1R inhibitor, WEE1 inhibitor
    AZD1775 + avapritinib
    25
    FGFR inhibitor, PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, c-KIT inhibitor
    imatinib + infigratinib
    26
    c-KIT inhibitor
    IDRX-42
    No biomarker
    KIT mutation
    KIT exon 13 mutation
    KIT exon 11 mutation
    KIT exon 17 mutation
    KIT exon 18 mutation
    KIT exon 14 mutation
    KIT V654A
    KIT positive
    KIT expression
    KIT exon 17 mutation + KIT exon 18 mutation
    KIT exon 11 mutation + KIT exon 17 mutation
    KIT N822K
    KIT N820Y
    KIT V560E
    KIT V559_E561del
    KIT M552_V555delMYEV
    KIT W557_V559>F
    KIT W557_V559>C
    KIT Y823D
    KIT N822Y
    KIT D820A
    KIT D820G
    KIT D820Y
    KIT wild-type
    KIT W557_V559delinsF
    KIT D818Y
    KIT exon 9 mutation
    KIT exon 11 W557_K558delins
    KIT P577del + KIT W557Lfs*5 + KIT Y823D
    SDHB deletion
    SDHB mutation
    PDGFRA D842V
    PDGFRA I843_D846delIMHD
    PDGFRA mutation
    PDGFRA exon 18 mutation
    NTRK3 fusion
    HER-2 positive
    HER-2 negative
    NTRK2 fusion
    BRAF V600E
    NTRK1 fusion
    DEPDC5 deletion
    PD-L1 expression
    SDHC mutation
    TMEM127 mutation
    CDK4 overexpression
    APC mutation
    SDHB mutation + NF1 mutation
    KIT wild-type + SDHB deletion
    TP53 mutation
    SRC mutation
    KIT positive + CD34 positive + ANO1 positive + ACTA2 positive
    TP53 overexpression
    MDM2 overexpression
    FGF2 elevation
    TEKT4 mutation
    SUFU mutation
    GPR20 expression