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BIOMARKER:
FLT3 D835Y
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Associations
(12)
News
Trials
C2 | Sensitive
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C2 | Resistant
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Tyrosine Kinase Inhibitors
Serine-Threonine Kinase Inhibitors
Immunotherapy
FGF
Other
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Acute Myelogenous Leukemia
pexidartinib
C4
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
pexidartinib
imatinib
C4
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
imatinib
midostaurin
C2
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
midostaurin
sorafenib
C3
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
sorafenib
Max-40279
D
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
Max-40279
ponatinib
D
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
ponatinib
gilteritinib
D
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
gilteritinib
MLN518
D
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
MLN518
SU5614
D
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
SU5614
BGS-2456
D
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
BGS-2456
quizartinib
C3
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
quizartinib
sunitinib
C3
FLT3 D835Y
|
Acute Myelogenous Leukemia
|
sunitinib
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