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BIOMARKER:

EZH2 mutation

i
Other names: EZH2, ENX-1, EZH1, KMT6, KMT6A, Enhancer of zeste 2 polycomb repressive complex 2 subunit




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Include preclinical:
Follicular Lymphoma
Diffuse Large B Cell Lymphoma
Acute Myelogenous Leukemia
Myelodysplastic Syndrome
Lymphoma
azacitidine
tazemetostat
venetoclax
valemetostat
CPI-169
rituximab
CPI-169 + CPI-203
SHR-2554
chidamide + SHR-2554
EED inhibitor
USP47 inhibitor