Group by Gene: Include preclinical: Tyrosine Kinase Inhibitors Epigenetics CD Protein Inhibitors Immune Checkpoint Inhibitors Immunotherapy Cyclin Dependent Kinase Inhibitors Serine-Threonine Kinase Inhibitors Hormone Therapy EGFR | HER2 inhibitor trastuzumab | WEE1 inhibitor ZN-c3 | AZD1775 | PD1 inhibitor nivolumab | pembrolizumab | CDK4 inhibitor, CDK6 inhibitor abemaciclib | Aromatase inhibitor letrozole | HER2 inhibitor, HER4 inhibitor, EGFR inhibitor afatinib | Immunotherapy Immunotherapy | HER2 inhibitor, EGFR inhibitor lapatinib | trastuzumab + lapatinib |
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No biomarker | |||||||||||
HER-2 expression | |||||||||||
HER-2 overexpression | |||||||||||
HER-2 positive | |||||||||||
HER-2 amplification | |||||||||||
ER positive | |||||||||||
MSI-H/dMMR | |||||||||||
MSH2 deletion | |||||||||||
MLH1 deletion | |||||||||||
MSH6 F1088fs | |||||||||||
ARID1A mutation |