BIOMARKER:

EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation

C4 | Sensitive

C4 | Resistant

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EGFR

Tyrosine Kinase Inhibitors

Lung Adenocarcinoma

osimertinib + gefitinib

EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation|Lung Adenocarcinoma|osimertinib + gefitinib

icotinib

EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation|Lung Adenocarcinoma|icotinib

bevacizumab + osimertinib

EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation|Lung Adenocarcinoma|bevacizumab + osimertinib

bevacizumab + icotinib

EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation|Lung Adenocarcinoma|bevacizumab + icotinib