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BIOMARKER:
DNMT3A mutation + FLT3-ITD mutation
i
Other names:
DNMT3A, DNA Methyltransferase 3 Alpha, DNA (Cytosine-5-)-Methyltransferase 3 Alpha, DNA (Cytosine-5)-Methyltransferase 3A, DNA MTase HsaIIIA, DNA Cytosine Methyltransferase 3A2, DNA Methyltransferase HsaIIIA, DNMT3A2, Dnmt3a, FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Associations
(4)
News
Trials
C3 | Sensitive
C4 | Sensitive
C3 | Resistant
C4 | Resistant
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Drug categories
Chemotherapy
DNA
Tyrosine Kinase Inhibitors
BCL Inhibitors
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Acute Myelogenous Leukemia
gilteritinib
C3
DNMT3A mutation + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
gilteritinib
quizartinib
C3
DNMT3A mutation + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
quizartinib
venetoclax
C4
DNMT3A mutation + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
venetoclax
cytarabine
C3
DNMT3A mutation + FLT3-ITD mutation
|
Acute Myelogenous Leukemia
|
cytarabine
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