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BIOMARKER:
CD74-ROS1 fusion
i
Other names:
CD74, DHLAG, ROS1, ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, V-Ros Avian UR2 Sarcoma Virus Oncogene Homolog 1, C-Ros Oncogene 1 Receptor Tyrosine Kinase, Proto-Oncogene Tyrosine-Protein Kinase ROS, Proto-Oncogene C-Ros-1, MCF3, ROS, V-Ros UR2 Sarcoma Virus Oncogene Homolog 1 (Avian), ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, Transmembrane Tyrosine-Specific Protein Kinase, Receptor Tyrosine Kinase C-Ros Oncogene 1, C-Ros Receptor Tyrosine Kinase, Proto-oncogene C-Ros, C-Ros-1
Associations
(10)
News
Trials
C2 | Sensitive
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C2 | Resistant
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Tyrosine Kinase Inhibitors
Chemotherapy
DNA
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Lung Adenocarcinoma
Non Small Cell Lung Cancer
Malignant Pleural Mesothelioma
Lung Cancer
crizotinib
C4
CD74-ROS1 fusion
|
Lung Adenocarcinoma
|
crizotinib
C3
CD74-ROS1 fusion
|
Non Small Cell Lung Cancer
|
crizotinib
C4
CD74-ROS1 fusion
|
Malignant Pleural Mesothelioma
|
crizotinib
AB-106
C2
CD74-ROS1 fusion
|
Non Small Cell Lung Cancer
|
AB-106
cisplatin + pemetrexed
C4
CD74-ROS1 fusion
|
Lung Adenocarcinoma
|
cisplatin + pemetrexed
entrectinib
C4
CD74-ROS1 fusion
|
Lung Adenocarcinoma
|
entrectinib
lorlatinib
C4
CD74-ROS1 fusion
|
Lung Adenocarcinoma
|
lorlatinib
pemetrexed
C4
CD74-ROS1 fusion
|
Lung Adenocarcinoma
|
pemetrexed
repotrectinib
C4
CD74-ROS1 fusion
|
Non Small Cell Lung Cancer
|
repotrectinib
gilteritinib
D
CD74-ROS1 fusion
|
Lung Cancer
|
gilteritinib
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