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    BIOMARKER:

    CD34 positive + BMI1 overexpression + MAP2K1 elevation

    i
    Other names: CD34, CD34 Molecule, CD34 Antigen, Hematopoietic Progenitor Ce, BMI1, PCGF4, RNF51, BMI1 proto-oncogene, polycomb ring fingerll Antigen CD34, MAP2K1, MAPKK1, MEK1, PRKMK1, Mitogen-activated protein kinase kinase 1
    Associations
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    Include preclinical:
    Acute Myelogenous Leukemia
    trametinib + BMIi-1