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BIOMARKER:
BRCA1 mutation + TMB-H
i
Other names:
TMB | Tumor Mutational Burden, BRCA1, BRCC1, PPP1R53, RNF53, Breast cancer 1, early onset
Associations
(3)
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Trials
C3 | Sensitive
C4 | Sensitive
C3 | Resistant
C4 | Resistant
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Drug categories
Immunotherapy
CD Protein Inhibitors
Immune Checkpoint Inhibitors
PARP Inhibitors
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Pancreatic Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Non Small Cell Lung Cancer
pembrolizumab + olaparib
C4
BRCA1 mutation + TMB-H
|
Pancreatic Adenocarcinoma
|
pembrolizumab + olaparib
C4
BRCA1 mutation + TMB-H
|
Pancreatic Ductal Adenocarcinoma
|
pembrolizumab + olaparib
Immunotherapy
C3
BRCA1 mutation + TMB-H
|
Non Small Cell Lung Cancer
|
Immunotherapy
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