^
    BIOMARKER:

    BRAF V600E

    i
    Other names: BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1




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    Include preclinical:
    Colorectal Cancer
    Melanoma
    Cutaneous Melanoma
    Astrocytoma
    Non Small Cell Lung Cancer
    Glioblastoma
    Ganglioglioma
    Thyroid Gland Carcinoma
    Colon Cancer
    Thyroid Gland Anaplastic Carcinoma
    Multiple Myeloma
    Glioma
    Thyroid Gland Papillary Carcinoma
    Neuroendocrine Tumor
    Hairy Cell Leukemia
    Solid Tumor
    Pancreatic Cancer
    Ovarian Cancer
    Biliary Tract Cancer
    Pancreatic Ductal Adenocarcinoma
    Cholangiocarcinoma
    Lung Adenocarcinoma
    Gastric Cancer
    Ovarian Serous Adenocarcinoma
    Prolymphocytic Leukemia
    Gastrointestinal Stromal Tumor
    Uveal Melanoma
    Synovial Sarcoma
    Ocular Melanoma
    Gastroesophageal Junction Adenocarcinoma
    Esophageal Squamous Cell Carcinoma
    Triple Negative Breast Cancer
    Breast Cancer
    Chronic Myeloid Leukemia
    Small Intestinal Carcinoma
    Neurofibrosarcoma
    Head and Neck Cancer
    Lymphoma
    Pancreatic Adenocarcinoma
    Ampulla of Vater Carcinoma
    Salivary Gland Cancer
    Esophageal Adenocarcinoma
    Thyroid Gland Medullary Carcinoma
    trametinib + dabrafenib
    cobimetinib
    vemurafenib
    panitumumab + encorafenib
    pembrolizumab
    nivolumab
    dabrafenib
    vemurafenib + cobimetinib
    cetuximab + trametinib + dabrafenib
    trametinib + dabrafenib + panitumumab
    binimetinib + encorafenib
    trametinib
    encorafenib
    BVD-523
    cetuximab + encorafenib
    ABM-1310
    BGB-283
    LY3214996
    selumetinib
    pembrolizumab + trametinib + dabrafenib
    cetuximab + vemurafenib
    bevacizumab
    trametinib + vemurafenib
    bortezomib
    trametinib + dabrafenib + everolimus
    siltuximab
    dabrafenib + rituximab
    cetuximab + binimetinib + encorafenib
    cediranib
    cisplatin + dacarbazine
    nivolumab + ipilimumab
    ASN007
    trifluridine/tipiracil
    ERAS-254 + LTT462
    dabrafenib + panitumumab
    vemurafenib + rituximab
    GDC-0941
    FCN-159
    regorafenib
    vemurafenib + XL888
    erlotinib + vemurafenib
    sorafenib + panitumumab
    entrectinib
    JSI-1187
    cetuximab + encorafenib + PF-07284892
    rivoceranib
    pembrolizumab + binimetinib + encorafenib
    durvalumab
    cetuximab + sorafenib
    vemurafenib + panitumumab
    ipilimumab
    nivolumab + cetuximab + encorafenib
    trametinib + dabrafenib + PDR001
    DAY101
    trametinib + dabrafenib + AT13387
    pembrolizumab + vemurafenib + cobimetinib
    trametinib + dabrafenib + MCS110
    atezolizumab + vemurafenib + cobimetinib
    cetuximab + vemurafenib + camrelizumab
    CI-1040
    CB-006-3
    panitumumab
    PLX4720 + axitinib
    pazopanib
    dabrafenib + axitinib
    lapatinib + PLX4720
    sorafenib
    AZ 628
    selumetinib + AZD8055
    BAY86-9766
    temsirolimus + BAY86-9766
    ponatinib + PLX4720
    U0126
    PD-0325901
    JQ-1
    GDC 0879
    BMS-754807
    PF-07284890
    RG6185
    trametinib + dabrafenib + AZD1775
    encorafenib + S63845
    everolimus + dichloroacetate topical
    cetuximab + dasatinib
    cetuximab + encorafenib + ASN007
    PHI-501
    alemtuzumab
    venetoclax
    dasatinib
    cisplatin + irinotecan
    bevacizumab + vemurafenib
    PLX4720
    KRT-232
    encorafenib + FORE-8394
    FORE-8394
    cetuximab
    palbociclib + PLX4720
    palbociclib
    AZD1775
    selumetinib + MK-2206
    SB-590885
    vemurafenib + selumetinib
    vemurafenib + MK-2206
    DEL-22379
    LY3009120
    TAK‐632
    PLX4720 + TAK‐632
    3PO
    VTX-11e
    trametinib + dasatinib
    dasatinib + SCH772984
    dasatinib + selumetinib
    VIC
    PD1 inhibitor + CTLA4 inhibitor
    Immunotherapy
    BRAF inhibitor
    EGFR inhibitor + BRAF inhibitor
    EGFR inhibitor
    Tyrosine kinase inhibitor
    mFOLFOX6
    BRAF inhibitor + MEK inhibitor
    FGFR inhibitor
    MEK inhibitor + pan-RAF inhibitor
    MAPK inhibitor
    Angiogenesis inhibitor