^
    BIOMARKER:

    BRAF mutation

    i
    Other names: BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1




    Show legend

    Include preclinical:
    Melanoma
    Colorectal Cancer
    Non Small Cell Lung Cancer
    Thyroid Gland Anaplastic Carcinoma
    Thyroid Gland Papillary Carcinoma
    Ovarian Cancer
    Mucosal Melanoma
    Multiple Myeloma
    Glioma
    Cholangiocarcinoma
    Thyroid Gland Carcinoma
    Chronic Lymphocytic Leukemia
    Cutaneous Melanoma
    Pancreatic Cancer
    Solid Tumor
    Renal Cell Carcinoma
    Anaplastic Astrocytoma
    Lung Adenocarcinoma
    Colon Cancer
    Rectal Cancer
    Ocular Melanoma
    Acute Myelogenous Leukemia
    Prostate Cancer
    Breast Cancer
    Thyroid Gland Medullary Carcinoma
    vemurafenib
    trametinib + dabrafenib
    FORE-8394 + cobicistat
    bevacizumab
    ramucirumab
    zanubrutinib
    tovorafenib
    dabrafenib
    cobimetinib + RG6185
    selumetinib
    regorafenib
    crizotinib + vemurafenib
    ziv-aflibercept IV
    cetuximab
    nivolumab + ipilimumab
    FOLFIRI + cetuximab
    ipilimumab
    KIN-2787
    panitumumab
    binimetinib + encorafenib
    VS-6766
    BVD-523
    trametinib
    atezolizumab + cobimetinib
    nivolumab
    pembrolizumab
    nivolumab + bevacizumab
    vemurafenib + cobimetinib
    cobimetinib
    trametinib + dabrafenib + ABT 263
    FORE-8394
    dabrafenib + KRT-232
    trametinib + dabrafenib + durvalumab
    AS703026
    venetoclax + cobimetinib
    vemurafenib + sorafenib
    trametinib + KRT-232
    selumetinib + RTB101
    atezolizumab + vemurafenib
    cetuximab + selumetinib
    pembrolizumab + INCB024360
    cisplatin + dacarbazine
    cisplatin + temozolomide
    nivolumab + trametinib + dabrafenib
    cetuximab + encorafenib
    temozolomide + rivoceranib
    EOS-448
    LTT462
    trametinib + dabrafenib + panitumumab
    ERAS-601
    BGB324
    imatinib
    ARN22089
    CB-228
    PLX4720
    SCH772984
    LY3009120
    SY-5609
    ABT 263 + AZD8055
    CI-1040
    vemurafenib + dabrafenib + encorafenib
    SU6656
    PP2
    RTB101 + RAF265
    RG6185
    RTB101
    SJ-C1044
    enzalutamide capsule
    sotorasib + IMM-1-104
    binimetinib + OKI-179
    encorafenib + OKI-179
    selumetinib + KRT-232
    durvalumab
    DS03090629
    GDC-0084
    dabrafenib + DS03090629
    gilteritinib
    dabrafenib + ivosidenib
    dabrafenib + SCH772984
    MEK inhibitor + TA99
    Immunotherapy
    PD1 inhibitor
    PD1 inhibitor + BRAF inhibitor
    PD1 inhibitor + BRAF inhibitor + MEK inhibitor
    VRD
    PD1 inhibitor + STAT3 inhibitor
    PD-L1 inhibitor
    BRAF inhibitor
    BRAF inhibitor + MEK inhibitor
    BRAF inhibitor + PLK1 inhibitor
    MEK inhibitor
    PD1 inhibitor + CTLA4 inhibitor
    EGFR inhibitor