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CANCER:

Adrenal Cortex Carcinoma





Show legend
Group by Gene:
Include preclinical:

0
DNA synthesis inhibitor
cisplatin
streptozocin
1
Steroid receptor inhibitor
mitotane
2
PD1 inhibitor
pembrolizumab
3
DNA synthesis inhibitor, Steroid receptor inhibitor
mitotane + streptozocin
4
Topoisomerase II inhibitor, Tubulin polymerization promoter, DNA synthesis inhibitor, Steroid receptor inhibitor, Lewis Y-related antigen-targeted antibody-drug conjugate
cisplatin + carboplatin + etoposide IV + mitotane + SGN-15
5
Topoisomerase II inhibitor, DNA synthesis inhibitor
cisplatin + etoposide IV
cisplatin + doxorubicin hydrochloride + etoposide IV
6
Topoisomerase II inhibitor, Tubulin polymerization promoter, Steroid receptor inhibitor
carboplatin + etoposide IV + mitotane
carboplatin + doxorubicin hydrochloride + etoposide IV + mitotane
7
Topoisomerase II inhibitor, Tubulin polymerization promoter
carboplatin + doxorubicin hydrochloride + etoposide IV
carboplatin + etoposide IV
8
Topoisomerase II inhibitor, DNA synthesis inhibitor, Steroid receptor inhibitor
cisplatin + etoposide IV + mitotane
cisplatin + doxorubicin hydrochloride + etoposide IV + mitotane
9
FGFR2 inhibitor, FGFR inhibitor, FGFR1 inhibitor, FGFR3 inhibitor, FGFR4 inhibitor
erdafitinib
10
CDK4 inhibitor, CDK6 inhibitor, CDK9 inhibitor
DSP-2033
11
EZH2 inhibitor, Steroid receptor inhibitor
mitotane + EZH2 inhibitor
12
Chemotherapy
EDP
13
DNA topoisomerase inhibitor
rubitecan
teniposide
14
Topoisomerase II inhibitor
mitoxantrone
SA033
15
CDK4 inhibitor, CDK6 inhibitor
palbociclib
16
Topoisomerase II inhibitor, DNA inhibitor
etoposide oral
17
DNA topoisomerase inhibitor, RNA synthesis inhibitor
pirarubicin
18
Aurora kinase inhibitor, Topoisomerase II inhibitor
SA033 + AMG 900
19
Topoisomerase II inhibitor, DNA cross linking agent
idarubicin hydrochloride
20
Topoisomerase II inhibitor, DNA intercalator
daunorubicin
21
DNA intercalator
aclarubicin
22
Aurora kinase inhibitor, Steroid receptor inhibitor
mitotane + AMG 900
23
Aurora kinase inhibitor
AMG 900
24
Multi-tyrosine kinase inhibitor
cabozantinib capsule
No biomarker
MSI-H/dMMR
RRM1 underexpression
TMB-L
MSH2 mutation
FGFR3-TACC3 fusion
TOP2A overexpression
CDK1 overexpression
CDK4 overexpression
AURKA overexpression
AURKB overexpression
MET overexpression
CDK2 overexpression
EZH2 overexpression
ASXL1 overexpression