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Association details:
| Biomarker: | YWHAE-JAZF1 fusion |
|---|---|
| Cancer: | Leiomyosarcoma |
| Drug: | Stivarga (regorafenib) (Multi-tyrosine kinase inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
RNA Sequencing for Personalized Treatment of Metastatic Leiomyosarcoma: Case Report
Published date:
08/30/2021
Excerpt:
Here we report a case of a 65-years-old female patient with metastatic UL...Regorafenib administration resulted in a complete metabolic response which lasted for 10 months. In addition, RNA sequencing analysis revealed a novel cancer fusion transcript of YWHAE gene with fusion partner JAZF1.
DOI:
https://doi.org/10.3389/fonc.2021.666001
