We ordered the sensitivity of the seven cell lines with adavosertib according to the IC50...The statistical relationships analyzed with Pearson’s correlation coefficient (Figure 4B) showed that Wee1 expression had a significant correlation (R = 0.871, p = 0.011) with adavosertib sensitivity....Adavosertib sensitivity was associated with lower Wee1 protein levels in thyroid cancer cell lines. Our data suggest that thyroid cancer cell lines with lower Wee1 expression rely on Wee1 activity, and interrupting Wee1 with adavosertib impairs cell growth more significantly than thyroid cancer cells with higher Wee1 expression.