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    Association details:
    Biomarker:TUBB3 overexpression
    Cancer:Non Small Cell Lung Cancer
    Drug:cisplatin (DNA synthesis inhibitor) +
    gemcitabine (DNA synthesis inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    Source:
    Asian Pac J Cancer Prev
    Title:

    Predictive and Prognostic Value of TUBB3, RRM1, APE1, and Survivin Expression in Chemotherapy-Receiving Patients with Advanced Non‑Small Cell Lung Cancer

    Published date:
    09/29/2023
    Excerpt:
    In the Cis/Gem regimen, only high TUBB3 expression was associated with poor overall survival...
    DOI:
    10.31557/APJCP.2023.24.9.3003