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Association details:
| Biomarker: | TUBB3 overexpression |
|---|---|
| Cancer: | Gastric Cancer |
| Drug: | docetaxel (Tubulin polymerization promoter, Microtubule stabilizer) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Association of high TUBB3 with resistance to adjuvant docetaxel-based chemotherapy in gastric cancer: translational study of ITACA-S
Published date:
06/11/2020
Excerpt:
...patients with high TUBB3 had a clinically meaningful poorer OS when receiving docetaxel-based versus 5-FU/LV chemotherapy (5-year OS 31% vs 54%; p = 0.09), with a statistically significant interaction between TUBB3 and treatment (p = 0.049).
Secondary therapy:
Chemotherapy
DOI:
10.1177/0300891620930803
