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Association details:
| Biomarker: | TSPAN6 positive |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Erbitux (cetuximab) (EGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer
Published date:
09/28/2021
Excerpt:
Importantly, Tspan6-positive patients with tumors in the proximal colon (right-sided) and those with KRAS mutations had a better response to Cetuximab than the patients that expressed low Tspan6 levels.
DOI:
https://doi.org/10.1073/pnas.2011411118