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Association details:
| Biomarker: | TRPV6 overexpression |
|---|---|
| Cancer: | Pancreatic Cancer |
| Drug: | gemcitabine (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
854 / 12 - A pharmaco-pheno-multiomic integration analysis of pancreatic cancer: A highly predictive biomarker model of biomarkers of Gemcitabine/Abraxane sensitivity and resistance
Published date:
03/15/2023
Excerpt:
Tumors exhibiting Gemcitabine/Abraxane resistance associate with increased TRPV6 RNA expression, MUC13 protein expression, and USP42 mutation among others.
