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Association details:
Biomarker:
TP73 overexpression
Cancer:
Multiple Myeloma
Drug:
epirubicin
(
Topoisomerase II inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
EHA 2023
Title:
DNP73 PROMOTES DRUG RESISTANCE AND IMMUNE EVASION IN MULTIPLE MYELOMA BY MODULATING MYC/CD47 AXIS
Published date:
05/11/2023
Excerpt:
DNp73 overexpression promoted the proliferation of MM cells, and induced the resistance to epirubicin treatment.
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