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Association details:
Biomarker:
TP53 mutation
Cancer:
Small Lymphocytic Lymphoma
Drug:
Rituxan (rituximab)
(
CD20 inhibitor
) +
lenalidomide
(
TNFα inhibitor
,
IL-6 inhibitor
,
IL-12 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Chronic lymphocytic leukemia/Small lymphocytic lymphoma: Suggested treatment regimens...CLL/SLL with del(17p)/TP53 mutation…relapsed/refractory therapy…other recommended regimens…lenalidomide ± rituximab
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