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Association details:
| Biomarker: | TP53 mutation |
|---|---|
| Cancer: | Lymphoma |
| Drug Class: | T-lymphocyte cell therapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
THE RESULTS OF THERAPY IN PATIENTS WITH B-CELL LYMPHOID MALIGNANCIES WITH MUTATIONS IN THE TP53 GENE
Published date:
05/12/2021
Excerpt:
P53 mutations were detected in 18 of 95 patients (19%)...One patient with «double-hit» lymphoma underwent CAR-T cell therapy. With a follow-up period of 6 months, the patient remain in complete remission.
