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    Association details:
    Biomarker:TP53 expression
    Cancer:Ovarian Cancer
    Drug:carboplatin (Tubulin polymerization promoter) +
    paclitaxel (Bcl2 inhibitor, Tubulin polymerization promoter)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C4 – Case Studies
    Source:
    Gan To Kagaku Ryoho
    Title:

    Ovarian Carcinosarcoma Associated with Cowden Syndrome-A Case Report

    Published date:
    07/01/2022
    Excerpt:
    Immunohistochemically, tumor cells were positive for p53. She was diagnosed with stage ⅢC ovarian carcinosarcoma….She received paclitaxel/ carboplatin chemotherapy. However, no response was observed and she died of disease 2 months postoperatively.