^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Title:

TOP2A is overexpressed in and a therapeutic target for adrenocortical carcinoma

Excerpt:
...TOP2A mRNA expression was significantly higher in ACC than in benign and normal adrenocortical tissue samples (p < 0.001)…Eleven of 14 TOP2A inhibitors had an antiproliferative effect in the NCI-H295R ACC cell line...
DOI:
10.1530/ERC-12-0403