^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

1174 Pharmacologic Inhibition of B Cell-Receptor-Associated Kinases with CG-806 Induces Apoptosis and Metabolic Reprogramming in Aggressive Non-Hodgkin Lymphoma (NHL) Models

Published date:
11/04/2020
Excerpt:
Treatment with CG-806, but not ibrutinib, induced apoptosis of primary MCL cells in CD40L- or BAFF-expressing stromal co-cultures...These results provide rationale for further investigation of CG-806 in aggressive NHL.