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Association details:
| Biomarker: | TNFRSF1B overexpression |
|---|---|
| Cancer: | Chronic Lymphocytic Leukemia |
| Regimen: | FCR (cyclophosphamide + fludarabine IV + Rituxan (rituximab)) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
EXPRESSION OF THE GENES OF THE MAIN RECEPTORS AND LIGANDS OF THE EXTERNAL PATHWAY OF APOPTOSIS IN PATIENTS WITH NEWLY DIAGNOSED CHRONIC LYMPHOCYTIC LEUKEMIA DURING RFC THERAPY
Published date:
05/17/2018
Excerpt:
Highest level of FAS, TRAIL and TNFR2 is associated with sensitivity oh B-CLL cells to induction of apoptosis. Moreover, it associated with better effectiveness RFC-therapy.
