^
Association details:
Biomarker:TNFRSF1B overexpression
Cancer:Chronic Lymphocytic Leukemia
Regimen: (cyclophosphamide + fludarabine IV + Rituxan (rituximab))
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

EXPRESSION OF THE GENES OF THE MAIN RECEPTORS AND LIGANDS OF THE EXTERNAL PATHWAY OF APOPTOSIS IN PATIENTS WITH NEWLY DIAGNOSED CHRONIC LYMPHOCYTIC LEUKEMIA DURING RFC THERAPY

Published date:
05/17/2018
Excerpt:
Highest level of FAS, TRAIL and TNFR2 is associated with sensitivity oh B-CLL cells to induction of apoptosis. Moreover, it associated with better effectiveness RFC-therapy.