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    Association details:
    Biomarker:TNFRSF1A rs10519613
    Cancer:Non Small Cell Lung Cancer
    Drug Class:EGFR inhibitor
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    Source:
    Front Oncol
    Title:

    Association of Polymorphisms in Inflammation Genes With the Prognosis of Advanced Non-Small Cell Lung Cancer Patients Receiving Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

    Published date:
    03/18/2022
    Excerpt:
    Forty-seven SNPs were genotyped in 318 advanced NSCLC patients receiving EGFR-TKIs….In single variant analyses, 3 SNPs (rs10519613, rs4819554, and rs4149570) were significantly associated with worse PFS.
    DOI:
    10.3389/fonc.2022.836117