^
Association details:
| Biomarker: | TNFRSF17 expression |
|---|---|
| Cancer: | Multiple Myeloma |
| Drug: | ACLX-001 (BCMA-targeted CAR-T immunotherapy) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Abstract 1549: ACLX-001, a novel BCMA-targeted CAR-T cell therapy that can be activated, silenced, and reprogrammed in vivo with soluble protein adapters in a dose dependent manner
Published date:
07/01/2021
Excerpt:
ACLX-001 demonstrated dose- and schedule-dependent in vivo efficacy in disseminated BCMA-expressing tumor models in NSG immunocompromised mice.
DOI:
10.1158/1538-7445.AM2021-1549
