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Association details:
Biomarker:
TNFA overexpression
Cancer:
Glioblastoma
Drug:
Avastin (bevacizumab)
(
VEGF-A inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Acta Neuropathol Commun
Title:
TNFa secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy
Published date:
04/14/2021
Excerpt:
...we show that high TNFα expression predicts worse response to Bevacizumab in GBM patients.
DOI:
10.1186/s40478-021-01163-0
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