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    Association details:
    Biomarker:TLR9 expression
    Cancer:Solid Tumor
    Drug:7-Hydroxystaurosporine (UCN-01) (AKT inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    New
    Source:
    Biomed Res Int
    Title:

    Comprehensive Bioinformatics Analysis of Toll-Like Receptors (TLRs) in Pan-Cancer

    Published date:
    07/28/2022
    Excerpt:
    The expression of TLR9 was significantly positively correlated with the drug sensitivity of fluphenazine, alectinib, carmustine, and 7-hydroxystaurosporine. TLR7 was significantly positively correlated with the drug sensitivity of alectinib….Our study reveals the significant role of TLRs family in pan-cancer and provides potential therapeutic strategies of cancer.
    DOI:
    10.1155/2022/4436646