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Association details:
Biomarker:TLR9 expression
Cancer:Solid Tumor
Drug:fluphenazine (DRD2 antagonist, DRD1 antagonist)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Title:

Comprehensive Bioinformatics Analysis of Toll-Like Receptors (TLRs) in Pan-Cancer

Published date:
07/28/2022
Excerpt:
The expression of TLR9 was significantly positively correlated with the drug sensitivity of fluphenazine, alectinib, carmustine, and 7-hydroxystaurosporine. TLR7 was significantly positively correlated with the drug sensitivity of alectinib….Our study reveals the significant role of TLRs family in pan-cancer and provides potential therapeutic strategies of cancer.
DOI:
10.1155/2022/4436646