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Association details:
| Biomarker: | THBS1 expression |
|---|---|
| Cancer: | Hepatocellular Cancer |
| Drug: | gemcitabine (DNA synthesis inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Serum thrombospondin-1 serves as a novel biomarker and agonist of gemcitabine-based chemotherapy in intrahepatic cholangiocarcinoma
Published date:
12/16/2022
Excerpt:
The expression level of TSP1 could reflect the sensitivity of ICC patients to gemcitabine chemotherapy....we found a key molecule-TSP1-that can predict and improve the sensitivity of ICC patients to gemcitabine chemotherapy, which is of great significance for the treatment of advanced cholangiocarcinoma.
DOI:
10.1038/s41416-022-02101-0
