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Association details:
Biomarker:
TFRC overexpression + PD-L1 underexpression
Cancer:
Non Small Cell Lung Cancer
Drug:
Opdivo (nivolumab)
(
PD1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Cancers (Basel)
Title:
Nivolumab after Induction Chemotherapy in Previously Treated Non-Small-Cell Lung Cancer Patients with Low PD-L1 Expression
Published date:
09/07/2023
Excerpt:
Higher baseline TFRC levels predicted a favorable response to nivolumab in NSCLC with low PD-L1 expression.
DOI:
https://www.mdpi.com/2072-6694/15/18/4460
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