^
Association details:
Biomarker:TERT 124C>T
Cancer:Glioblastoma
Drug Class:PD1 inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

214 The effect of Anti-PD-1 therapy on median overall survival and progression free survival in glioblastoma multiforme patients with certain tumor markers

Published date:
11/09/2020
Excerpt:
Upon analyzing the data the presence of a TERT promoter 124C>T mutation, IDH wildtype, and lower TMB gave much better OS and PFS after treatment in patients on Anti-PD1 therapy.
DOI:
10.1136/jitc-2020-SITC2020.0214