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Association details:
| Biomarker: | TAF15-NR4A3 fusion |
|---|---|
| Cancer: | Soft Tissue Sarcoma |
| Drug: | sunitinib (c-KIT inhibitor, VEGFR inhibitor, PDGFR inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Activity of sunitinib in extraskeletal myxoid chondrosarcoma
Excerpt:
From July 2011, 10 patients with progressive metastatic translocated EMC have been consecutively treated with sunitinib...refractory cases carried the alternative TAF15-NR4A3 fusion.
DOI:
10.1016/j.ejca.2014.03.013
