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    Association details:
    Biomarker:STRBP-JAK2 fusion
    Cancer:B Acute Lymphoblastic Leukemia
    Drug Class:T-lymphocyte cell therapy
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C4 – Case Studies
    Source:
    Front Oncol
    Title:

    Identification of STRBP as a Novel JAK2 Fusion Partner Gene in a Young Adult With Philadelphia Chromosome-Like B-Lymphoblastic Leukemia

    Published date:
    01/11/2021
    Excerpt:
    ...a novel STRBP-JAK2 fusion gene in a 21-year-old woman with Ph-like ALL...autologous chimeric antigen receptor (CAR) T cells against both CD19 and CD22, which induced morphologic remission
    DOI:
    10.3389/fonc.2020.611467