^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Title:

The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer

Excerpt:
Similarly, GSK2126458, the dual PI3K and mTORC1/2 inhibitor, showed a significant difference in sensitivity between LKB1 wild-type and LKB1-mutant cell lines (Fig. 2B [p = 0.0105 according to the Wilcoxon rank sum test]).
DOI:
10.1016/j.jtho.2019.02.019