Evidence Level:Sensitive: A2 - Guideline
Title:
SSAs (octreotide or lanreotide) are recommended for SSTR-positive and/or functional metastatic G1-grade 2 (G2) GI-NETs…
Excerpt:SSAs (octreotide or lanreotide) are recommended for SSTR-positive and/or functional metastatic G1-grade 2 (G2) GI-NETs…
Evidence Level:Sensitive: A2 - Guideline
New
Excerpt:SSAs can be recommended as first-line therapy for tumour growth control in advanced, slowly-growing SSTR-positive GI and Pan-NETs up to a Ki-67 of 10% [I,A; ESMO-MCBS v1.1 score: 3] for lanreotide and [I, A; ESMO-MCBS v1.1 score: 2] for octreotide.
Evidence Level:Sensitive: A2 - Guideline
New
Excerpt:Bronchopulmonary/Thymus Neuroendocrine Tumors…Pancreatic Neuroendocrine Tumors (Well-Differentiated Grade 1/2): Preferred Regimens...Octreotide, LAR or lanreotide (if SSR-positive and/or hormonal symptoms).
Evidence Level:Sensitive: B - Late Trials
Title:
1096O - Lanreotide autogel/depot (LAN) in patients with advanced bronchopulmonary (BP) neuroendocrine tumors (NETs): Results from the phase III SPINET study
Excerpt:SPINET evaluated LAN in advanced somatostatin receptor (SSTR)-positive TC and AC BP-NETs…Median (95% CI) PFS in the LAN randomized group was 16.6 (12.8–21.9) months…
Evidence Level:Sensitive: C2 – Inclusion Criteria
New
Title:
Circulating Tumour Cells in Somatuline Autogel Treated NeuroEndocrine Tumours Patients
Excerpt:...- Patients must have had either a positive somatostatin receptor scintigraphy result or a positive 68Gallium-DOTATATE PET imaging result....
Evidence Level:Sensitive: C2 – Inclusion Criteria
New
Title:
A Retrospective Data Analysis of Therapy With PRRT Combined With Lanreotide Autogel® for Neuroendocrine Tumours
Excerpt:...- Confirmed presence of Somatostatin Receptors (SSTRs) on all target lesions based on positive SSTR scintigraphy (Octreoscan®/99mTC-tektrotyd) or 68Ga SSTR Positron Emission Tomography-Computerised Tomography (PET/CT) imaging, i.e. Grade ≥2 respectively per the Krenning scale or per the modified Krenning scale...
More C2 evidence
Evidence Level:Sensitive: C2 – Inclusion Criteria
New
Title:
Efficacy and Safety Study in Pancreatic or Midgut Neuroendocrine Tumours Having Progressed Radiologically While Previously Treated With Lanreotide Autogel® 120 mg
Excerpt:...- Positive somatostatin receptors type 2...
Evidence Level:Sensitive: C2 – Inclusion Criteria
New
Title:
Efficacy and Safety of Lanreotide Autogel/ Depot 120 mg vs. Placebo in Subjects With Lung Neuroendocrine Tumours
Excerpt:...- Positive Somatostatin receptors (SSTR) imaging...