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Association details:
Biomarker:SSTR positive
Cancer:Neuroendocrine Tumor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
Source:
Title:

Systemic Therapy for Tumor Control in Metastatic Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors: ASCO Guideline

Published date:
09/29/2023
Excerpt:
SSAs (octreotide or lanreotide) are recommended for SSTR-positive and/or functional metastatic G1-grade 2 (G2) GI-NETs…
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
Excerpt:
Bronchopulmonary/Thymus Neuroendocrine Tumors…Pancreatic Neuroendocrine Tumors (Well-Differentiated Grade 1/2): Preferred Regimens...Octreotide, LAR or lanreotide (if SSR-positive and/or hormonal symptoms).
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
Excerpt:
SSAs can be recommended as first-line therapy for tumour growth control in advanced, slowly-growing SSTR-positive GI and Pan-NETs up to a Ki-67 of 10% [I,A; ESMO-MCBS v1.1 score: 3] for lanreotide and [I, A; ESMO-MCBS v1.1 score: 2] for octreotide.