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    Association details:
    Biomarker:SNHG5 overexpression
    Cancer:Gastric Cancer
    Drug:cisplatin (DNA synthesis inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    New
    Source:
    Eur Rev Med Pharmacol Sci
    Title:

    LncRNA SNHG5 promotes cisplatin resistance in gastric cancer via inhibiting cell apoptosis

    Excerpt:
    We detected the expressions of SNHG5, apoptosis-specific genes (Bax and Bcl-2) and drug resistance-specific genes (MDR1 and MRP1) in cisplatin-sensitive and cisplatin-resistant GC patients….Compared with cisplatin-sensitive GC patients, SNHG5 expression was remarkably higher in cisplatin-resistant GC patients.
    DOI:
    10.26355/eurrev_201905_17921