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Association details:
Biomarker:SMO mutation
Cancer:Non Small Cell Lung Cancer
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers

Published date:
11/03/2022
Excerpt:
In the NSCLC discovery cohort, the median progression-free survival in the SMO mutant (SMO_MUT) was longer than that in the wild type (SMO_WT) (23.0 vs. 3.8 months, adjusted p = 0.041).
DOI:
https://doi.org/10.3389/fimmu.2022.955800