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Association details:
Biomarker:
SMARCB1 A240fsX28
Cancer:
Sarcoma
Drug:
Ibrance (palbociclib)
(
CDK4 inhibitor
,
CDK6 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ASCO 2021
Title:
Next generation sequencing of sarcomas: Response to crizotinib in two cases with MET amplification.
Published date:
05/19/2021
Excerpt:
Table summarizes matched therapies in responders....Sarcoma...SMARCB1: A240fs*28...Palbociclib – SD, 6 mo...Tazemetostat – SD, 2 yrs
DOI:
10.1200/JCO.2021.39.15_suppl.11538
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