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Association details:
| Biomarker: | SLFN11 expression |
|---|---|
| Cancer: | Acute Lymphocytic Leukemia |
| Drug: | Aqupla (nedaplatin) (DNA synthesis inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
The first evidence for SLFN11 expression as an independent prognostic factor for patients with esophageal cancer after chemoradiotherapy
Published date:
11/20/2020
Excerpt:
...Human leukemia CCRF-CEM SLFN11-proficient [parent]...cells were highly sensitive to carboplatin and nedaplatin compared to SLFN11-deficient cells...in vitro study, SLFN11-proficient cells were highly sensitive to platinum derivatives compared to SLFN11-deficient cells...Figure S1
