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Association details:
| Biomarker: | SLC6A19 rs4975596 |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Erbitux (cetuximab) (EGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway
Excerpt:
Significant association with in vitro cetuximab response was observed for SLC6A19 SNPs rs7736074 and rs4975596 (P = 0.003 and 0.002 respectively).
DOI:
10.1186/1755-8794-6-43