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Association details:
| Biomarker: | SERPINE1 expression |
|---|---|
| Cancer: | Ovarian Serous Adenocarcinoma |
| Drug: | Mekinist (trametinib) (MEK inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
3242 / 11 - The role of SERPINE1 in trametinib resistance in low-grade ovarian serous cancer cell line
Published date:
03/09/2022
Excerpt:
...the measurement of plasma SERPINE1 in LGOSC mouse model and cancer patient revealed that SERPINE1 could be a predictive marker in cancer diagnosis and prognosis...SERPINE1 gene expression level correlated with trametinib sensitivity and patient survival.
