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Association details:
| Biomarker: | SEMA7A overexpression |
|---|---|
| Cancer: | Estrogen Receptor Positive Breast Cancer |
| Drug: | fulvestrant (Selective estrogen receptor degrader) |
| Direction: | Resistant |
Evidence:
Source:
Title:
P54-42 - Hormonal Regulation of Semaphorin 7a Promotes Therapeutic Resistance in Breast Cancer
Published date:
01/21/2021
Excerpt:
...in ER+ cell lines, overexpression of SEMA7A promotes in vitro growth in the face of estrogen-deprivation, tamoxifen, or fulvestrant treatments.
