^
Association details:
Biomarker:SEMA7A expression
Cancer:Breast Cancer
Drug:Venclexta (venetoclax) (Bcl2 inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

Abstract 60: Semaphorin 7a promotes cell survival and resistance to endocrine therapy in ER+ breast cancer

Published date:
05/15/2020
Excerpt:
...patients with high Semaphorin 7a expression be considered as candidates for the addition of Venetoclax, an FDA approved Bcl2 targeted therapy, to their current therapeutic regimen...
DOI:
10.1158/1538-7445.AM2020-60