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Association details:
| Biomarker: | SALL4 positive + POU5F1 positive + KIT positive + PLAA positive |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | etoposide IV (Topoisomerase II inhibitor) + bleomycin (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
[Pathological features of primary extragonadal germ cell tumor of the prostate with small round blue cell morphology]
Published date:
02/01/2021
Excerpt:
The immunohistochemistry (IHC) stains of SALL4, OCT3/4, CD117 and PLAP were all positive…Based on these IHC findings and the morphology, the two cases were diagnosed as primary seminoma of the prostate, which were consequently treated with six cycles of bleomycin, etoposide and cisplatin-based chemotherapy. A complete response was achieved in case 1.
DOI:
10.3760/cma.j.cn112151-20200421-00334
