^
Association details:
Biomarker:SAA1 underexpression
Cancer:Glioma
Drug:temozolomide (DNA synthesis inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

SAA1 knockdown promotes the apoptosis of glioblastoma cells via downregulation of AKT signaling

Published date:
03/10/2021
Excerpt:
Moreover, Gliomas with low SAA1 expression have increased sensitivity to Temozolomide (TMZ)...Our study strongly suggested that SAA1 was a regulator of cells apoptosis...a novel biomarker of sensitivity of glioma to TMZ.
DOI:
10.7150/jca.48419